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Sorafenib br Fig Zeta potentials of
2019-10-22
Fig. 5. Zeta potentials of DOX-DHHC-GNRAH at different pH values. Fig. 6. Cumulative release profiles of DOX from DOX-DHHC-GNRAH at different pH values. 3.6. In vitro cellular uptake Effective cellular uptake of DOX-DHHC-GNRAH in cancer Sorafenib is a prerequisite for efficient combined photo
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GSK126 br Cell apoptosis analysis br Apoptosis
2019-10-21
2.8. Cell apoptosis analysis Apoptosis of breast cancer GSK126 treated with different drugs was determined using Beyotime Annexin V-FITC apoptosis detection Kit and a FACScalibur flow cytometer (Becton Dickinson, San Jose, CA, USA) according to the instructions. Breast cancer cells were seeded
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br In vivo therapeutic study
2019-10-21
3.7. In vivo therapeutic study and safety evaluation We further investigated the therapeutic performance of [email protected] NPs using MDA-MB-231 human breast tumor-bearing nude mice. The mice were treated with free DOX, free OA, FA-CS-g-OA or [email protected] NPs (7.5 mg DOX equiv./kg) after tumor
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br characterizations are shown in Fig
2019-10-16
characterizations are shown in Fig. S4). Characterization of the con-jugates is shown in Figs. S2, S5–S7. TubA/SpG molar ratio was 0.9 as determined after TubA release by DTT treatment and TubA quantifi-cation by RP-HPLC (Fig. S8). A TubA derivative with a 3-pyridyldithio propionate reactive gr
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br Patients with VI may require for stronger
2019-10-15
Patients with VI may require for stronger adjuvant therapies because of the high risk of recurrence. Conflicts of interest The authors have declared that no conflict of interest exists. Acknowledgment References [16] N. Pathmanathan, R.L. Balleine, Ki67 and proliferation in breast c
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br Some degree of adhesion
2019-10-14
Some degree of adhesion and arrest of tumor BCI-121 within vessels occurs simply as a result of mechanical factors especially blood flow of target location [32]. For one thing, consistent with the anatomy evi-dence, veins in the pancreas drain into the splenic, the inferior and superior mesenteri
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br Statistical analysis of TMA data br
2019-10-14
Statistical analysis of TMA data Descriptive statistics were performed for patientsÕ characteristics. Frequencies, means, and range values are given. Association of RORg(t) expression with categorical variables was performed using the Chi-square or FisherÕs Exact test, where appropriate, while
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br Akin O Sala E Moskowitz CS et al Transition
2019-10-14
7. Akin O, Sala E, Moskowitz CS, et al. Transition zone prostate cancers: features, detection, localization, and staging at endorectal MR imaging. Radiology 2006; 239:784–792. 9. Verma S, Rajesh A, Morales H, et al. Assessment of aggressiveness of pros-tate cancer: correlation of apparent Paxil
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br breastcancer org Stages of Breast Cancer Available from h
2019-10-12
[29] breastcancer.org. Stages of Breast Cancer; Available from: http://www. breastcancer.org/symptoms/diagnosis/staging. [30] The University of Texas MD Anderson Cancer Center. Cancer Treatment Algo-rithms [cited 2017 September 13]; Available from: https://www.mdanderson. org/for-physicians/cli
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on a given day In other words
2019-10-08
on a given day. In other words, since the cancer center has high correlation analysis and the level of significance of the correlations variability in the patient mix, this constraint permits the mathe- This multicollinearity limited the analysis because this effect matical model to change
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br Vapnik V Golowich S E
2019-10-08
Vapnik, V., Golowich, S.E., Smola, A., 1996. Support vector method for function approximation, regression estimation, and signal processing. Annu. Conf. Neural Inf. Process. Syst., 281–287 Vidyasagar, M., 2017. Machine learning methods in computational cancer biology. Yang, Fan et al., 2017. L
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Dalbavancin br nucleus to cytoplasm in hCerECs suggesting th
2019-10-08
nucleus to cytoplasm in hCerECs, suggesting the transcriptional activity of IRF3 and NFkB1 was inhibited in YAP- and YAPS127A- overexpressed Dalbavancin (Figures 4F, S8A, and S8B). Consistent with in vitro results, critical genes involved in viral recognition signaling, such as TLR2, MYD88
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br We show that IDEA can comprehensively
2019-10-07
We show that IDEA can comprehensively identify several types of genetic alterations with clinical relevance including: single nucleotide variants, insertions and deletions, gene copy number alterations, and rearrangements. To test IDEA in the clinical setting, we exploited an annotated set of samp
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Not only the sensitivity but selectivity is another major fa
2019-10-07
Not only the sensitivity, but selectivity is another major factor for a sensor to be used in bio-imaging. To investigate the selectivity of the CPF nanoprobe towards FA, we have performed the fluorescence re-sponse of the probe toward various potentially coexisting substances, such as Na+, K+, Zn2+,
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br development In this study we identified di erentially
2019-10-07
development. In this study we identified 129 differentially expressed miRNAs, among which five miRNAs are associated with the OS of pa-tients with GC. In addition, the target genes of these five miRNAs were screened, and bioinformatics analysis was used to predict their biolo-gical functions and