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br changes other sequences might be needed Diffusion weighte
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changes, other sequences might be needed. Diffusion weighted MR imaging (DWI) visualises restriction in water mobility in tissue. Micro-environmental pathologic conditions such as the content of malignant tumour tissue change the water mobility and could be used as an early biomarker of response t
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br Monocytes macrophages promote stemness
2020-08-30
3.5. Monocytes/macrophages promote stemness and the EMT of PDAC cells As cancer progresses, tumor Relebactam may reprogram the surrounding cells to create a supportive microenvironment that facilitates their growth and metastasis. Monocyte and derived macrophages determine the initiation and m
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br The cytotoxicity of C curetum
2020-08-28
The cytotoxicity of C. curetum on the HeLa cell line was significantly induced by 0.125 mg/ml of the C. curetum acetone fraction (p ≤ 0.0001) by approximately 90%, while 10 mg/mL of the C. curetum aqueous fraction significantly induced cytotoxicity (p ≤ 0.0001) by Porcine pancreatic lipase inhi
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br M Touillaud et al site was obtained
2020-08-28
M. Touillaud, et al. site was obtained from the national network of cancer registries (FRANCIM). Age-, sex- and site-specific incidence rates were computed and applied to the 2015 national French population to obtain an esti-mate of the national number of new cases in that year. 2.4. Statistical
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HBX 41108 br Infection Main Main factor s for Carcinogenic m
2020-08-28
Infection Main Main factor(s) for Carcinogenic mechanism(s)b Gold standard for Cancers with sufficient Cancers with limited transmission transmission From Bouvard 2009 detection evidencec evidencec route(s) Hepatitis B HBX 41108 (HBV), Sera and other Reusing needles, Inflam
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br Next we investigated the expression levels of integrin
2020-08-28
Next, we investigated the expression levels of integrin β3 in normal breast tissue samples, ductal carcinoma in situ (DCIS), and in invasive and metastatic breast tumour tissues by qRT-PCR and IHC staining. We found that integrin β3 was undetectable or under-expressed in normal mammary tissues, bu
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br Peipins L A et al Radiographic
2020-08-28
Peipins, L.A., et al., 2003. Radiographic abnormalities and exposure to asbestos-con-taminated vermiculite in the Anthranilic Acid of Libby, Montana, USA. Environ. Health Perspect. 111, 1753–1759. Price, B., 2008. Exposure to airborne amphibole structures and health risks: libby, Montana. Regul.
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br Statistical analysis br The
2020-08-28
Statistical analysis The statistical analyses were performed with IBM SPSS (version 25, IBM Corp., Armonk, NY, USA). Normality was tested with the ShapiroeWilk test. Normally distributed continuous variables were assessed by Student's t-test and reported as the mean ± standard deviation. Ca
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br ADT treated men had and lower
2020-08-18
ADT-treated men had 7.2% and 7.8% lower lumbar spine aBMD compared to PCa (P = 0.037) and healthy controls (P = 0.010), re-spectively (Table 2). While there was a significant main effect for total hip aBMD between groups (P = 0.040), corrected pairwise comparisons revealed only a trend for lower (
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br Trastuzumab has radically changed the clinical scenario i
2020-08-18
Trastuzumab has radically changed the clinical scenario in the adjuvant treatment of eBC (leading to a durable 40% reduction of the relative risk of recurrence and to 34% fewer death).6,7 It is noteworthy that no clinical or preclinical evidences support the 12-months duration whose choice was bas
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KPT-185 br PEITC Fig S a The corresponding morphology of
2020-08-18
PEITC (Fig. S10a). The corresponding morphology of RBCs was shown in Fig. S10b–f, which could be found that a few RBCs have a morpho-logic change that was due to the influence of DOX. APTT, PT and TT time (Fig. S10g–i) of BPNs-PDA-PEG-PEITC/DOX were close to the control which indicated that the
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br Penetration efficiency in multicellular
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2.2.5.2. Penetration efficiency in GSK-3 tumor spheroids. The internalization of targeted and non-targeted dendrimer conjugates into the spheroids was studied using confocal microscopy. F-G4-PEG-Biotin and F-G4-PEG were added to the spheroids grown in 8-well glass chamber slides and incubated for
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br In spite of recent advances
2020-08-18
In spite of recent advances in chemotherapy and radiotherapy, surgical operation remains the only potential curative treatment for pancreatic cancer [66,67]. Novel therapeutic agents have so far not yet been developed, which may be ascribed partially to a lack of proper models that represent the t
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Trichostatin A br ACCEPTED MANUSCRIPT br Importantly TAF ina
2020-08-18
ACCEPTED MANUSCRIPT Importantly, TAF inactivation led to a partial reversal of stromal desmoplasia, partial normalization of tumor vasculature, decreased tumoral hypoxia, and improved tumor growth delay. They have used similar targeted NPs to modulate TAF-mediated cytokine signaling119. CXCL12
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E64 br In vitro photothermal e ciency and controlled drug re
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3.2. In vitro photothermal efficiency and controlled drug release of PMDIs To explore the photothermal efficiency of PMDIs, changes in tem-perature were tracked in vitro in the presence of laser irradiation by a thermal imaging camera. When irradiated for 5 min at 1 W cm−2, the temperatures of PBS,